Description

4-Fluoro-3-(n-Propylcarbamoyl)Benzeneboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a fluoro-substituted aromatic ring and a propylcarbamoyl moiety, enabling precise molecular construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in the creation of complex, fluorinated target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, including potential kinase inhibitors, receptor antagonists, and other bioactive molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the fluorine atom and specific side chain enhance biological activity and stability.
• Material Science: Employed in the creation of advanced organic materials, such as ligands for catalysts or monomers for specialty polymers.
• Suzuki-Miyaura Cross-Coupling: Primarily utilized as a boronic acid coupling partner to form biaryl and other carbon-carbon bonds in complex molecule assembly.
• Chemical Synthesis: Serves as a versatile building block in medicinal and process chemistry for introducing specific fluorinated aromatic segments.
• R&D Laboratories: A valuable reagent for academic and industrial research focused on organoboron chemistry and fluorine chemistry.

Basic Information

Item	Detail
Product Name	4-Fluoro-3-(n-Propylcarbamoyl)Benzeneboronic Acid
CAS No.	874219-32-6
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	4-Fluoro-3-(propylcarbamoyl)phenylboronic Acid; 3-Carbamoyl-4-fluorobenzeneboronic Acid, N-propyl-; [4-Fluoro-3-(propylaminocarbonyl)phenyl]boronic Acid; B-[4-Fluoro-3-[(propylamino)carbonyl]phenyl]boronic Acid; 874219-32-6; 4-Fluoro-3-propylcarbamoylbenzeneboronic Acid; 3-(N-Propylcarbamoyl)-4-fluorobenzeneboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3-(n-Propylcarbamoyl)Benzeneboronic Acid is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with industry standards. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.