Description

4-Fluoro-3-(Piperidin-1-Ylcarbonyl)Benzeneboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring both a boronic acid group and a fluorinated piperidine carbonyl moiety, makes it an invaluable reagent for constructing complex molecules via cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid partner for forming carbon-carbon bonds, enabling the construction of biaryl and heterobiaryl structures common in drug molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom and the piperidine group can enhance biological activity and stability.
• Material Science & OLED Development: Employed in the synthesis of advanced organic materials, including ligands for catalysts and fluorescent molecules for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and tools for studying biological processes and enzyme functions.

Basic Information

Product Name	4-Fluoro-3-(Piperidin-1-Ylcarbonyl)Benzeneboronic Acid
CAS No.	874219-30-4
Molecular Formula	C13H17BFNO3
Molecular Weight	265.09 g/mol
Synonyms	[4-Fluoro-3-(piperidine-1-carbonyl)phenyl]boronic acid; 3-Carbamoyl-4-fluorobenzeneboronic acid, N-piperidyl-; 4-Fluoro-3-(1-piperidinylcarbonyl)benzeneboronic Acid; B-[4-Fluoro-3-(1-piperidinylcarbonyl)phenyl]boronic acid; 874219-30-4; Boronic acid, B-[4-fluoro-3-(1-piperidinylcarbonyl)phenyl]-; AKOS BRN-0791; FT-0770507
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3-(Piperidin-1-Ylcarbonyl)Benzeneboronic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥95% (by HPLC), with options for higher grades available. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and other critical parameters is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.