Description

3-(tert-Butylcarbamoyl)-4-Fluorobenzeneboronic Acid is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its core value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected amide moiety, enabling precise molecular construction. This compound is essential for researchers and manufacturers in pharmaceutical R&D, agrochemical development, and materials science, particularly for creating complex fluorinated aromatic structures with specific amide linkages.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems and amide bonds.
• Suzuki-Miyaura Cross-Coupling Reagent: The boronic acid functionality enables efficient carbon-carbon bond formation with aryl/vinyl halides, crucial for constructing complex biaryl structures in drug discovery.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that benefit from fluorinated aromatic components.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as fluorinated polymers and small molecules for OLEDs or semiconductors.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	3-(tert-Butylcarbamoyl)-4-Fluorobenzeneboronic Acid
CAS No.	874219-26-8
Molecular Formula	C11H15BFNO3
Molecular Weight	239.06 g/mol
Synonyms	4-Fluoro-3-((tert-butylcarbamoyl))benzeneboronic Acid; 3-(N-tert-Butylcarbamoyl)-4-fluorobenzeneboronic Acid; (3-((tert-Butylcarbamoyl))-4-fluorophenyl)boronic Acid; 4-Fluoro-3-(tert-butylaminocarbonyl)phenylboronic Acid; B-[3-[(1,1-Dimethylethyl)amino]carbonyl]-4-fluorophenyl]boronic Acid; 874219-26-8; 3-(tert-Butylcarbamoyl)-4-fluorophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3-(tert-Butylcarbamoyl)-4-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere if possible to maintain long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.