Description

4-Fluoro-3-(2-Hydroxyethylcarbamoyl)Benzeneboronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both a boronic acid group and a fluoro-substituted aromatic ring, makes it a valuable reagent for cross-coupling reactions, particularly in the synthesis of complex pharmaceutical intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, functionalized boronic acids for precision synthesis. We supply this material with a focus on consistent quality and reliable batch-to-batch performance to support your R&D and production scale-up needs.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides that require specific fluorinated aromatic components.
• Material Science Research: Employed in the creation of organic electronic materials, such as those used in OLEDs and sensors, where its boronic acid group facilitates polymerization or functionalization.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes targeting specific proteins or enzymes.
• Ligand Synthesis for Catalysis: Serves as a starting material for synthesizing sophisticated ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific custom synthesis projects requiring this unique boronic acid scaffold.

Basic Information

Product Name	4-Fluoro-3-(2-Hydroxyethylcarbamoyl)Benzeneboronic Acid
CAS No.	874219-25-7
Molecular Formula	C9H11BFNO4
Molecular Weight	226.99 g/mol
Synonyms	4-Fluoro-3-[(2-hydroxyethyl)carbamoyl]benzeneboronic Acid; [4-Fluoro-3-[(2-hydroxyethyl)carbamoyl]phenyl]boronic Acid; 3-Carbamoylethyl-4-fluorobenzeneboronic Acid; B-[4-Fluoro-3-[(2-hydroxyethyl)aminocarbonyl]phenyl]boronic Acid; 874219-25-7; 4-Fluoro-3-(2-hydroxyethylaminocarbonyl)phenylboronic Acid; 4-Fluoro-3-(N-2-hydroxyethylcarbamoyl)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3-(2-Hydroxyethylcarbamoyl)Benzeneboronic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.