Description

3-(Benzylcarbamoyl)-4-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, particularly the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in advanced material science for creating functional organic frameworks.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or linker in the creation of advanced organic polymers, covalent organic frameworks (COFs), and other functional materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel boron-containing catalysts and ligands for asymmetric synthesis.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in cross-coupling chemistry and boronic acid chemistry.

Basic Information

Product Name	3-(Benzylcarbamoyl)-4-Fluorobenzeneboronic Acid
CAS No.	874219-22-4
Molecular Formula	C14H13BFNO3
Molecular Weight	273.07 g/mol
Synonyms	4-Fluoro-3-[(phenylmethyl)carbamoyl]benzeneboronic Acid; [3-(Benzylcarbamoyl)-4-fluorophenyl]boronic Acid; 3-Carbamoyl-4-fluorobenzeneboronic Acid Benzyl Ester; B-[3-[(Benzylamino)carbonyl]-4-fluorophenyl]boronic Acid; 874219-22-4; 3-Benzylcarbamoyl-4-fluorophenylboronic Acid; N-Benzyl-4-fluoro-3-boronobenzamide
EINECS	Contact for details

Quality Control

Every batch of 3-(Benzylcarbamoyl)-4-Fluorobenzeneboronic Acid is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive applications like pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.