Description

3-Fluoro-4-(4-Morpholinyl)Benzeneboronic Acid Pinacol Ester is a high-value, synthetically versatile organoboron building block. This compound matters for its critical role as a key intermediate in modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by pharmaceutical and agrochemical R&D teams, as well as advanced material scientists, for the synthesis of novel active ingredients and functional molecules. CAS No. 873431-46-0.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-targeted therapeutic research.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in next-generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, due to its conjugated boronate ester structure.
• Chemical Biology & Probe Development: Employed in the synthesis of bioconjugates and molecular probes for studying biological pathways and protein functions.
• Catalyst Ligand Precursor: Can be utilized to synthesize novel ligand systems for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring bespoke boronic acid derivatives.

Basic Information

Product Name	3-Fluoro-4-(4-Morpholinyl)Benzeneboronic Acid Pinacol Ester
CAS No.	873431-46-0
Molecular Formula	C16H23BFNO3
Molecular Weight	307.17 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-[3-fluoro-4-(morpholin-4-yl)phenyl]-1,3,2-dioxaborolane; 2-(3-Fluoro-4-morpholinophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Fluoro-4-morpholinophenylboronic Acid Pinacol Ester; (3-Fluoro-4-morpholinophenyl)boronic Acid Pinacol Ester; Pinacol 3-Fluoro-4-morpholinophenylboronate; 873431-46-0; Boronic acid, B-[3-fluoro-4-(4-morpholinyl)phenyl]-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(4-Morpholinyl)Benzeneboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analysis including HPLC for purity and identity confirmation via NMR and MS. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed in a dry environment to prevent hydrolysis of the boronate ester. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.