Description

Methyl 2-Amino-5-Iodo-4-(Trifluoromethyl)Benzoate is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. Its unique structure, featuring amino, iodo, and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Acts as a monomer or functionalizing agent for creating specialty polymers and liquid crystals with specific optical or electronic properties.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of molecular imaging agents.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions to introduce complex aromatic systems.
• Fluorine Chemistry: A valuable substrate for studying and applying fluorinated aromatic compounds in catalysis and medicinal chemistry.

Basic Information

Product Name	Methyl 2-Amino-5-Iodo-4-(Trifluoromethyl)Benzoate
CAS No.	872624-52-7
Molecular Formula	C9H7F3INO2
Molecular Weight	345.06 g/mol
Synonyms	Methyl 2-Amino-5-iodo-α,α,α-trifluoro-p-toluate; 2-Amino-5-iodo-4-(trifluoromethyl)benzoic Acid Methyl Ester; Benzoic acid, 2-amino-5-iodo-4-(trifluoromethyl)-, methyl ester; Methyl 2-amino-α,α,α-trifluoro-5-iodo-p-toluate; 5-Iodo-2-amino-4-trifluoromethylbenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Amino-5-Iodo-4-(Trifluoromethyl)Benzoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.