Description

3-Ethoxy-5-(Trifluoromethyl)Benzeneboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) containing the trifluoromethyl and ethoxy pharmacophores, which are prevalent in drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating functional organic molecules used in electronic displays and optoelectronic devices.
• Polymer & Material Science: Incorporated into specialty polymers to modify thermal stability, chemical resistance, and optical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for methodological development and the synthesis of complex, polyfunctional aromatic compounds.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to introduce the 3-ethoxy-5-(trifluoromethyl)phenyl moiety into target molecules.

Basic Information

Product Name	3-Ethoxy-5-(Trifluoromethyl)Benzeneboronic Acid
CAS No.	871332-96-6
Molecular Formula	C9H10BF3O3
Molecular Weight	233.98 g/mol
Synonyms	[3-Ethoxy-5-(trifluoromethyl)phenyl]boronic acid; (3-Ethoxy-5-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[3-ethoxy-5-(trifluoromethyl)phenyl]-; 3-Ethoxy-5-trifluoromethylbenzeneboronic acid; 5-Ethoxy-3-(trifluoromethyl)benzeneboronic acid; 3-Ethoxy-α,α,α-trifluoro-m-tolueneboronic acid; m-Ethoxy-α,α,α-trifluoromethylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-5-(Trifluoromethyl)Benzeneboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.