Description

(4-((4-Fluorobenzyl)Oxy)Phenyl)Boronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound matters as a critical building block in modern organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biphenyl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides through palladium-catalyzed coupling reactions.
• Material Science Research: Serves as a monomer or building block for developing organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the development of chemical probes, sensors, and affinity ligands due to its boronic acid functionality which can interact with diols.
• Academic & R&D Laboratories: A versatile reagent for methodological development in cross-coupling chemistry and the exploration of new synthetic pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke organic molecules on scale.

Basic Information

Product Name	(4-((4-Fluorobenzyl)Oxy)Phenyl)Boronic Acid
CAS No.	871125-82-5
Molecular Formula	C₁₃H₁₂BFO₃
Molecular Weight	246.05 g/mol
Synonyms	4-(4-Fluorobenzyloxy)phenylboronic acid; [4-[(4-Fluorophenyl)methoxy]phenyl]boronic acid; (4-((4-Fluorobenzyl)oxy)phenyl)boronic acid; 4-(4-Fluorobenzyloxy)benzeneboronic acid; B-[4-[(4-Fluorophenyl)methoxy]phenyl]boronic acid; 871125-82-5; (4-(4-Fluorobenzyloxy)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our (4-((4-Fluorobenzyl)Oxy)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.