Description

4-Propoxy-2,3,5,6-Tetrafluorobenzeneboronic Acid is a high-value organoboron building block, specifically a tetrafluorinated arylboronic acid derivative, critical for modern cross-coupling reactions. Its core value lies in enabling the precise synthesis of complex, fluorinated aromatic structures, which are highly sought after in advanced material and pharmaceutical research for their unique electronic and metabolic properties. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries who require reliable, high-purity intermediates for Suzuki-Miyaura and other palladium-catalyzed couplings.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated bioactive molecules, active pharmaceutical ingredients (APIs), and drug candidates, leveraging the benefits of fluorine substitution.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where fluorinated aromatic rings enhance stability and biological activity.
• Material Science Research: Serves as a precursor for creating fluorinated polymers, liquid crystals, and organic electronic materials (e.g., OLEDs, OFETs) with tailored properties.
• Suzuki-Miyaura Cross-Coupling Reactions: Primarily employed as a versatile boronic acid coupling partner to form carbon-carbon bonds with various aryl/heteroaryl halides.
• Chemical Biology & Probe Development: Utilized in synthesizing fluorinated molecular probes and tags for imaging and diagnostic applications.
• Academic & Industrial R&D: A fundamental reagent for methodological development in synthetic organic chemistry and scale-up process optimization.

Basic Information

Product Name	4-Propoxy-2,3,5,6-Tetrafluorobenzeneboronic Acid
CAS No.	871125-71-2
Molecular Formula	C9H9BF4O3
Molecular Weight	244.0 g/mol
Synonyms	(4-Propoxy-2,3,5,6-tetrafluorophenyl)boronic acid; 2,3,5,6-Tetrafluoro-4-propoxybenzeneboronic acid; 4-Propoxy-2,3,5,6-tetrafluorophenylboronic acid; B-(4-Propoxy-2,3,5,6-tetrafluorophenyl)boronic acid; Tetrafluoropropoxybenzeneboronic Acid; 871125-71-2; Boronic acid, B-(4-propoxy-2,3,5,6-tetrafluorophenyl)-
EINECS	Contact for details

Quality Control

Our 4-Propoxy-2,3,5,6-Tetrafluorobenzeneboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive coupling reactions. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon/nitrogen) for long-term storage to prevent decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.