Description

3-Ethoxy-2,4,6-Trifluorophenylboronic Acid is a high-purity, multi-fluorinated arylboronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides that benefit from the enhanced metabolic stability and bioavailability imparted by the trifluoroethoxy motif.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated organic electronic materials for displays and lighting, where it helps tune electronic properties and improve device performance.
• Polymer Science: Monomer for synthesizing specialty polymers with unique thermal, chemical, or optical properties via polymerization or post-polymerization functionalization.
• Chemical Research & Development: Versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Item	Details
Product Name	3-Ethoxy-2,4,6-Trifluorophenylboronic Acid
CAS No.	871125-69-8
Molecular Formula	C8H7BF3O3
Molecular Weight	210.95 g/mol
Synonyms	(3-Ethoxy-2,4,6-trifluorophenyl)boronic acid; 2,4,6-Trifluoro-3-ethoxybenzeneboronic acid; Boronic acid, B-(3-ethoxy-2,4,6-trifluorophenyl)-; 3-Ethoxy-2,4,6-trifluorobenzeneboronic acid; 871125-69-8; AKOS005258213; FT-0698303; SCHEMBL15506227; BRN 8785087
EINECS	Contact for details

Quality Control

Every batch of 3-Ethoxy-2,4,6-Trifluorophenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.