Description

2,4-Difluoro-3-Formylphenylboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl group and a boronic acid moiety on a difluorinated aromatic ring, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and monomers for specialty polymers.
• Chemical Biology & Probe Development: Utilized as a handle for bioconjugation and in the synthesis of molecular probes and sensors due to the reactivity of the boronic acid and aldehyde groups.
• Academic & Contract Research: Serves as a valuable reagent in academic laboratories and CROs (Contract Research Organizations) for method development and exploring new chemical spaces.

Basic Information

Product Name	2,4-Difluoro-3-Formylphenylboronic Acid
CAS No.	870718-06-2
Molecular Formula	C7H5BF2O3
Molecular Weight	185.92 g/mol
Synonyms	(3-Formyl-2,4-difluorophenyl)boronic acid; 2,4-Difluoro-3-formylbenzeneboronic acid; 3-Borono-2,4-difluorobenzaldehyde; 2,4-Difluorobenzaldehyde-3-boronic acid; (2,4-Difluoro-3-formylphenyl)boronic acid; Boronic acid, B-(2,4-difluoro-3-formylphenyl)-; 870718-06-2
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and adherence to ISO standards guarantee a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.