Description

6-Trifluoromethoxy-3-Indazolecarboxylic Acid CAS NO 869782-97-8 is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazole core functionalized with a trifluoromethoxy group. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted bioactivity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for oncology, central nervous system (CNS) disorders, and anti-inflammatory applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting protein kinases and other enzymatic pathways.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the indazole scaffold.
• Material Science: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic semiconductors.
• Contract Research & Development (CRO/CMO): Supplied to organizations for custom synthesis, process development, and scale-up projects.
• Academic Research: Utilized in universities and research institutes for medicinal chemistry programs and biochemical studies.

Basic Information

Product Name	6-Trifluoromethoxy-3-Indazolecarboxylic Acid
CAS No.	869782-97-8
Molecular Formula	C9H5F3N2O3
Molecular Weight	246.14 g/mol
Synonyms	6-(Trifluoromethoxy)-1H-indazole-3-carboxylic acid; 6-Trifluoromethoxyindazole-3-carboxylic Acid; 1H-Indazole-3-carboxylic acid, 6-(trifluoromethoxy)-; 869782-97-8; 6-Trifluoromethoxy-1H-indazole-3-carboxylic acid; 3-Indazolecarboxylic acid, 6-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethoxy-3-Indazolecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.