Description

2-(4-Fluoroanilino)Isonicotinic Acid is a high-purity organic intermediate featuring a fluorinated aniline moiety linked to an isonicotinic acid core. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, enabling the introduction of specific fluorine-containing pharmacophores. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the production chain of fluorinated APIs, ensuring precise molecular architecture.
• Ligand and Catalyst Development: Useful for creating specialized ligands in catalytic processes or as a component in metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(4-Fluoroanilino)Isonicotinic Acid
CAS No.	868734-50-3
Molecular Formula	C12H9FN2O2
Molecular Weight	232.21 g/mol
Synonyms	4-Fluoro-N-(4-pyridinyl)anthranilic Acid; 2-[(4-Fluorophenyl)amino]isonicotinic Acid; 2-(4-Fluoroanilino)pyridine-4-carboxylic Acid; Isonicotinic Acid, 2-(4-fluoroanilino)-; 868734-50-3; 2-(p-Fluoroanilino)isonicotinic Acid; 4-Pyridinecarboxylic acid, 2-[(4-fluorophenyl)amino]-
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoroanilino)Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.