Description

3-(Difluoromethoxy)-Benzeneboronic Acid is a specialized organoboron compound that serves as a versatile building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, which is critical for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, contributing to the development of new active ingredients.
• Material Science Research: Employed in the creation of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology: Acts as a probe or building block in the synthesis of molecules for biological target identification and validation.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	3-(Difluoromethoxy)-Benzeneboronic Acid
CAS No.	866607-09-2
Molecular Formula	C7H7BF2O3
Molecular Weight	187.94 g/mol
Synonyms	[3-(Difluoromethoxy)phenyl]boronic Acid; (3-Difluoromethoxyphenyl)boronic Acid; 3-Difluoromethoxybenzeneboronic Acid; Benzeneboronic acid, 3-(difluoromethoxy)-; m-(Difluoromethoxy)phenylboronic Acid; 3-(Difluoromethoxy)phenyl-B(OH)2; DFMPBA
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethoxy)-Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and reactivity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.