Description

(R)-tert-Butyl 5-Methyl-1,2,3-Oxathiazolidine-3-Carboxylate 2,2-Dioxide is a high-value chiral building block and a key intermediate in advanced organic synthesis. Its primary commercial value lies in its role as a precursor for the synthesis of complex pharmaceutical agents, particularly those targeting central nervous system disorders. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries who require high-purity, enantiomerically pure intermediates for API development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of novel therapeutic agents, particularly in neurology and psychiatry.
• Asymmetric Synthesis: Used as a building block to introduce stereochemical complexity in the synthesis of enantiomerically pure compounds.
• Process Chemistry: Employed in the development and optimization of scalable manufacturing routes for Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs.
• Chemical Biology Probes: Utilized in the synthesis of labeled or modified compounds for studying biological mechanisms.

Basic Information

Product Name	(R)-tert-Butyl 5-Methyl-1,2,3-Oxathiazolidine-3-Carboxylate 2,2-Dioxide
CAS No.	863453-61-6
Molecular Formula	C9H17NO5S
Molecular Weight	251.30 g/mol
Synonyms	(R)-5-Methyl-1,2,3-oxathiazolidine-3-carboxylic acid 2,2-dioxide, 1,1-dimethylethyl ester; (R)-tert-Butyl 5-methyl-1,2,3-oxathiazolidine-3-carboxylate S,S-dioxide; (R)-N-Boc-5-methyl-1,2,3-oxathiazolidine-2,2-dioxide; (R)-5-Methyl-3-((tert-butoxy)carbonyl)-1,2,3-oxathiazolidine 2,2-dioxide; (R)-tert-Butyl 5-methyl-2,2-dioxo-2λ⁶-1,2,3-oxathiazolidine-3-carboxylate
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 5-Methyl-1,2,3-Oxathiazolidine-3-Carboxylate 2,2-Dioxide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity (HPLC), and identity confirmation. We adhere to cGMP principles for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements for advanced API synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.