Description

(S)-3,3'-Di(Pyridin-2-Yl)-[1,1'-Binapthalene]-2,2'-Diol CAS NO 862856-02-8 is a high-purity, chiral binaphthol derivative featuring axially chiral 1,1'-binaphthyl and coordinating pyridyl groups. This compound serves as a sophisticated ligand and catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for R&D and manufacturing chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a privileged chiral ligand for transition metal-catalyzed reactions, including hydrogenation, C-C bond formation, and oxidation.
• Pharmaceutical Intermediate Synthesis: For the enantioselective synthesis of active pharmaceutical ingredients (APIs) and key chiral building blocks.
• Agrochemical Research: In the development of chiral pesticides and herbicides where specific stereochemistry is critical for activity.
• Material Science: As a building block for chiral polymers, sensors, and liquid crystals with advanced optical properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and organometallic chemistry.

Basic Information

Item	Details
Product Name	(S)-3,3'-Di(Pyridin-2-Yl)-[1,1'-Binapthalene]-2,2'-Diol
CAS No.	862856-02-8
Molecular Formula	C₃₄H₂₂N₂O₂
Molecular Weight	490.55 g/mol
Synonyms	(S)-3,3'-Bis(2-pyridyl)-1,1'-bi-2-naphthol; (S)-3,3'-Di(2-pyridyl)-BINOL; (S)-3,3'-Dipyridin-2-yl-[1,1'-binaphthalene]-2,2'-diol; (S)-VAPOL; (S)-3,3'-Dipyridyl-BINOL; (S)-3,3'-Bis(pyridin-2-yl)-1,1'-binaphthyl-2,2'-diol; (S)-3,3'-Di-2-pyridyl-1,1'-bi-2-naphthol
EINECS	Contact for details

Quality Control

Our (S)-3,3'-Di(Pyridin-2-Yl)-BINOL is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for chiral purity and assay, to ensure it meets the high standards required for catalytic and synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.