Description

2-[(4-Fluorobenzyl)Oxy]-3-Methoxybenzoic Acid is a high-purity, synthetic organic compound featuring a fluorinated benzyl ether moiety attached to a methoxybenzoic acid core. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research and fine chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated aromatic system and modifiable carboxylic acid group.
• Agrochemical Synthesis: Intermediate for developing new-generation herbicides, fungicides, or plant growth regulators that require fluorinated aromatic components for enhanced activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and functional polymers where the fluorine atom imparts specific chemical properties.
• Academic & Institutional Research: Used in universities and research institutes for exploratory organic synthesis and the development of new chemical methodologies.

Basic Information

Product Name	2-[(4-Fluorobenzyl)Oxy]-3-Methoxybenzoic Acid
CAS No.	861433-52-5
Molecular Formula	C15H13FO4
Molecular Weight	276.26 g/mol
Synonyms	3-Methoxy-2-[(4-fluorobenzyl)oxy]benzoic acid; 2-[(4-Fluorophenyl)methoxy]-3-methoxybenzoic acid; Benzoic acid, 2-[(4-fluorobenzyl)oxy]-3-methoxy-; 2-(4-Fluorobenzyloxy)-3-methoxybenzoic acid; 861433-52-5; 2-[(4-Fluorobenzyl)oxy]-3-methoxybenzoic acid; 3-Methoxy-2-(4-fluorobenzyloxy)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-[(4-Fluorobenzyl)Oxy]-3-Methoxybenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.