Description

Benzoic Acid, 3-Chloro-2-(Trifluoromethyl)- is a halogenated and fluorinated derivative of benzoic acid, offering a unique combination of steric and electronic properties for advanced chemical synthesis. This compound matters as a sophisticated building block, enabling the introduction of both chlorine and trifluoromethyl functional groups to modulate the reactivity, lipophilicity, and metabolic stability of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for enhanced bioactivity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group is a critical motif for efficacy.
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and as a precursor for corresponding acid chlorides, esters, and amides in fine chemical production.

Basic Information

Item	Detail
Product Name	Benzoic Acid, 3-Chloro-2-(Trifluoromethyl)-
CAS No.	857061-43-9
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	3-Chloro-2-(trifluoromethyl)benzoic acid; 2-Trifluoromethyl-3-chlorobenzoic acid; 3-Chloro-α,α,α-trifluoro-o-toluic acid; Benzoic acid, 3-chloro-2-(trifluoromethyl)-; 857061-43-9; 3-Chloro-2-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-Chloro-2-(Trifluoromethyl)- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.