Description

(1R)-1-(4-Ethoxyphenyl)Propylamine is a chiral amine building block of significant interest in advanced organic synthesis. This compound matters because its specific stereochemistry and functional groups make it a valuable intermediate for creating optically active molecules with targeted biological activity. Pharmaceutical research and development teams, particularly those in medicinal chemistry, need this high-purity intermediate for the synthesis of potential active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and receptor modulators.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Used in the synthesis of chiral active ingredients for crop protection products, where specific stereochemistry can influence efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands used in homogeneous catalysis, such as asymmetric hydrogenation.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	(1R)-1-(4-Ethoxyphenyl)Propylamine
CAS No.	856758-62-8
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	(R)-1-(4-Ethoxyphenyl)propan-1-amine; (R)-1-Amino-1-(4-ethoxyphenyl)propane; (1R)-1-(4-Ethoxyphenyl)-1-propylamine; (R)-4-Ethoxy-α-ethylbenzylamine; (R)-α-Ethyl-4-ethoxybenzenemethanamine; Dextrorotatory enantiomer of 1-(4-Ethoxyphenyl)propylamine
EINECS	Contact for details

Quality Control

Our (1R)-1-(4-Ethoxyphenyl)Propylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Products undergo rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification and standard identification tests. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.