Description

tert-Butyl 5-Amino-2-Fluorobenzoate is a high-purity fluorinated benzoate derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which combines a protected carboxylic acid group with an aromatic amine and fluorine substituent, enabling precise chemical modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical reactions involving fluorinated aromatics.

Basic Information

Product Name	tert-Butyl 5-Amino-2-Fluorobenzoate
CAS No.	853070-30-1
Molecular Formula	C11H14FNO2
Molecular Weight	211.24 g/mol
Synonyms	5-Amino-2-fluorobenzoic acid tert-butyl ester; 2-Fluoro-5-aminobenzoic acid tert-butyl ester; Benzoic acid, 5-amino-2-fluoro-, 1,1-dimethylethyl ester; tert-Butyl 5-amino-2-fluorobenzoate; 853070-30-1; 1,1-Dimethylethyl 5-amino-2-fluorobenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Amino-2-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP development and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.