Description

4-Carboxy-2-Fluorobenzeneboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in the unique combination of a reactive boronic acid group and a carboxylic acid moiety on a fluorinated aromatic ring, enabling precise cross-coupling and subsequent functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and advanced materials through Suzuki-Miyaura coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorine atom and boronic acid group enhance biological activity and stability.
• Material Science: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structure allows for fine-tuning of electronic properties.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and sensors due to its selective reactivity.
• Ligand for Catalysis: Can be utilized to synthesize complex ligands for transition metal catalysts used in asymmetric synthesis.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polymers with tailored functionalities.

Basic Information

Product Name	4-Carboxy-2-Fluorobenzeneboronic Acid
CAS No.	851335-07-4
Molecular Formula	C7H6BFO4
Molecular Weight	183.93 g/mol
Synonyms	2-Fluoro-4-carboxybenzeneboronic Acid; (4-Carboxy-2-fluorophenyl)boronic Acid; 4-Borono-3-fluorobenzoic Acid; 3-Fluoro-4-boronobenzoic Acid; 2-Fluoro-4-(dihydroxyboryl)benzoic Acid; Benzoic acid, 4-borono-3-fluoro-; F-C6H3-4-COOH-2-B(OH)2
EINECS	Contact for details

Quality Control

Every batch of 4-Carboxy-2-Fluorobenzeneboronic Acid is produced under a strict quality management system. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.