Description

4-Ethoxycarbonyl-2-Fluorophenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable organoboron building block, specifically a protected boronic acid ester. This compound is essential for facilitating efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental to modern pharmaceutical and advanced materials research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring fluorinated aromatic structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise molecular assembly is critical.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant boronate reagent for palladium-catalyzed carbon-carbon bond formation.
• Chemical Biology & Probe Development: Useful for synthesizing fluorinated molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers producing bespoke compounds for client projects.

Basic Information

Product Name	4-Ethoxycarbonyl-2-Fluorophenylboronic Acid, Pinacol Ester
CAS No.	851334-92-4
Molecular Formula	C15H20BFO4
Molecular Weight	294.13 g/mol
Synonyms	(4-(Ethoxycarbonyl)-2-fluorophenyl)boronic acid pinacol ester; 2-Fluoro-4-(ethoxycarbonyl)benzeneboronic acid pinacol ester; 4-Carbethoxy-2-fluorophenylboronic acid pinacol ester; 4-(Ethoxycarbonyl)-2-fluorobenzeneboronic acid pinacol ester; Pinacol [4-(ethoxycarbonyl)-2-fluorophenyl]boronate; 851334-92-4; Boronic acid, B-[4-(ethoxycarbonyl)-2-fluorophenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-Ethoxycarbonyl-2-Fluorophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.