Description

4-Carboxy-2-Fluorobenzeneboronic Acid, 97% is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its bifunctional nature, featuring both a boronic acid and a carboxylic acid group, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for Suzuki-Miyaura cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for creating biaryl and heterobiaryl structures via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic components.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs and sensors, where the fluorine atom modulates electronic properties.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors that target specific proteins or enzymes.
• Ligand Synthesis for Catalysis: Serves as a starting material for synthesizing sophisticated ligands used in asymmetric catalysis and other transition metal-catalyzed processes.

Basic Information

Product Name	4-Carboxy-2-Fluorobenzeneboronic Acid, 97%
CAS No.	851135-07-4
Molecular Formula	C7H6BFO4
Molecular Weight	183.93 g/mol
Synonyms	2-Fluoro-4-carboxybenzeneboronic Acid; (4-Carboxy-2-fluorophenyl)boronic Acid; 4-Borono-3-fluorobenzoic Acid; 3-Fluoro-4-boronobenzoic Acid; Benzoic acid, 4-borono-3-fluoro-; FCBBA; 2-Fluoro-4-(dihydroxyboryl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 4-Carboxy-2-Fluorobenzeneboronic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation, NMR for structural verification, and Karl Fischer titration for moisture content, to ensure it meets the specified 97% minimum purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF Titration)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.