Description

(2-Bromomethyl-4-Fluorobenzene)Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its dual functionality, offering both a reactive boronic acid group for Suzuki-Miyaura cross-coupling and a bromomethyl handle for further derivatization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to create novel fungicides and herbicides by incorporating the fluorinated benzyl moiety into lead structures.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where the fluorine atom enhances stability and performance.
• Chemical Biology Probes: Utilized in the creation of tagged molecules and activity-based probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(2-Bromomethyl-4-Fluorobenzene)Boronic Acid
CAS No.	850568-01-3
Molecular Formula	C7H7BBrFO2
Molecular Weight	232.85 g/mol
Synonyms	2-(Bromomethyl)-4-fluorobenzeneboronic Acid; (2-(Bromomethyl)-4-fluorophenyl)boronic Acid; 4-Fluoro-2-(bromomethyl)benzeneboronic Acid; B-(2-(Bromomethyl)-4-fluorophenyl)boronic Acid; 850568-01-3; 2-Bromomethyl-4-fluorophenylboronic Acid; 4-Fluoro-2-bromomethylphenylboronic Acid
EINECS	Contact for details

Quality Control

Our (2-Bromomethyl-4-Fluorobenzene)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.