Description

4-Fluoro-2-Hydroxyphenylboronic Acid is a versatile organoboron compound featuring both a boronic acid and a phenolic hydroxyl group on a fluorinated aromatic ring. This unique bifunctional structure makes it a valuable building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers developing pharmaceutical intermediates, agrochemicals, and advanced materials. The compound is supplied to meet the stringent requirements of R&D and industrial-scale production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing biaryl or fluorinated aromatic motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science: Building block for organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Research: Essential reagent in academic and industrial laboratories for method development and exploring new coupling methodologies.
• Dye & Pigment Industry: Intermediate for synthesizing specialized fluorinated dyes and pigments.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a boronic acid coupling partner to form carbon-carbon bonds with aryl halides.

Basic Information

Product Name	4-Fluoro-2-Hydroxyphenylboronic Acid
CAS No.	850568-00-2
Molecular Formula	C6H6BFO3
Molecular Weight	155.92 g/mol
Synonyms	(4-Fluoro-2-hydroxyphenyl)boronic acid; 2-Hydroxy-4-fluorobenzeneboronic acid; 4-Fluoro-2-hydroxybenzeneboronic acid; B-(4-Fluoro-2-hydroxyphenyl)boronic acid; 850568-00-2; 4-Fluoro-2-hydroxy phenylboronic acid; 4-Fluoro-2-hydroxybenzeneboronic acid; 4-Fluoro-2-hydroxy-phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2-Hydroxyphenylboronic Acid is produced and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards for identity, purity, and consistency. Comprehensive analytical methods including HPLC, NMR, and IR spectroscopy are employed. Certificates of Analysis (COA) detailing all specification results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.