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3-Amino-4-Chlorophenylboronic Acid, Pinacol Ester CAS NO 850567-56-5


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CAS No.:850567-56-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Amino-4-Chlorophenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, making it a reliable and versatile reagent for complex coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for the synthesis of novel active ingredients and functional molecules.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A key intermediate for constructing biaryl and heterobiaryl structures prevalent in drug discovery.
  • Pharmaceutical Intermediate: Used in the synthesis of potential drug candidates, including kinase inhibitors and other small molecule therapeutics.
  • Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
  • Materials Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers.
  • Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for catalysis and metal-organic frameworks (MOFs).
  • Chemical Biology Probes: Facilitates the creation of molecular probes for studying biological processes and target identification.

Basic Information

Product Name 3-Amino-4-Chlorophenylboronic Acid, Pinacol Ester
CAS No. 850567-56-5
Molecular Formula C12H17BClNO2
Molecular Weight 253.53 g/mol
Synonyms 3-Amino-4-chlorobenzeneboronic acid pinacol ester; 4-Chloro-3-aminophenylboronic acid pinacol ester; (3-Amino-4-chlorophenyl)boronic acid pinacol ester; 2-(3-Amino-4-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 850567-56-5; B-(3-Amino-4-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Amino-4-chloro-benzeneboronic acid pinacol ester
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Quality Control

Our production of 3-Amino-4-Chlorophenylboronic Acid, Pinacol Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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