Description

1-(4-Fluorophenyl)Vinylboronic Acid, Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its value lies in enabling the precise and efficient construction of complex fluorinated organic molecules, which are critical in advanced material and pharmaceutical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel fluorinated drug candidates, including kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the development of advanced fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or building block for creating fluorinated conjugated polymers and organic electronic materials for OLEDs and semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of fluorinated molecular probes and tags for imaging and diagnostic applications.
• Process Chemistry & Scale-up: Suitable for optimization and scale-up from laboratory to pilot plant scale for commercial production pathways.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new chemical spaces in fluoroorganic chemistry.

Basic Information

Product Name	1-(4-Fluorophenyl)Vinylboronic Acid, Pinacol Ester
CAS No.	850567-55-4
Molecular Formula	C14H18BFO2
Molecular Weight	248.10 g/mol
Synonyms	1-(4-Fluorophenyl)ethenylboronic acid pinacol ester; (1-(4-Fluorophenyl)vinyl)boronic acid pinacol ester; 4-Fluorostyrylboronic acid pinacol ester; 1-(p-Fluorophenyl)vinylboronic acid pinacol ester; B-[1-(4-Fluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 850567-55-4; Pinacol (1-(4-fluorophenyl)vinyl)boronate
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)Vinylboronic Acid, Pinacol Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and GC analysis, to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all relevant specifications are available upon request and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate for prolonged use to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.