Description

2-Methyl-4-(Trifluoromethoxy)Benzeneboronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the formation of carbon-carbon bonds via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing the trifluoromethoxy-phenyl moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aromatic frameworks.
• Material Science: Employed in the development of organic electronic materials, such as those used in OLEDs and semiconductors, via cross-coupling reactions.
• Ligand & Catalyst Development: Serves as a starting material for creating novel boron-containing ligands and catalysts for asymmetric synthesis.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and constructing complex molecular libraries.
• Liquid Crystal & Polymer Chemistry: Used as a monomer or intermediate in the synthesis of specialty polymers and liquid crystal materials.

Basic Information

Product Name	2-Methyl-4-(Trifluoromethoxy)Benzeneboronic Acid
CAS No.	850033-39-5
Molecular Formula	C8H8BF3O3
Molecular Weight	219.96 g/mol
Synonyms	[2-Methyl-4-(trifluoromethoxy)phenyl]boronic acid; 2-Methyl-4-(trifluoromethoxy)phenylboronic acid; 4-Trifluoromethoxy-o-tolylboronic acid; 2-Methyl-4-trifluoromethoxybenzeneboronic acid; Boronic acid, B-[2-methyl-4-(trifluoromethoxy)phenyl]-; 850033-39-5; 2-Methyl-4-(trifluoromethoxy)benzeneboronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(Trifluoromethoxy)Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.