Description

3-Fluoro-4-(Methylcarbamoyl)Benzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling its use as a versatile coupling partner in cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules for drug discovery and advanced material development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a fluorinated aromatic scaffold.
• Suzuki-Miyaura Cross-Coupling: Serves as a crucial boronic acid reagent for forming carbon-carbon bonds, enabling the construction of complex biaryl structures common in many modern therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated aromatic system.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CROs/CMOs serving the life sciences sector.

Basic Information

Product Name	3-Fluoro-4-(Methylcarbamoyl)Benzeneboronic Acid
CAS No.	849833-86-9
Molecular Formula	C9H11BFNO3
Molecular Weight	210.99 g/mol
Synonyms	3-Fluoro-4-(N-methylcarbamoyl)phenylboronic acid; (3-Fluoro-4-[(methylamino)carbonyl]phenyl)boronic acid; 4-Borono-2-fluoro-N-methylbenzamide; B-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]boronic acid; 849833-86-9; 3-Fluoro-4-methylcarbamoylbenzeneboronic acid; 2-Fluoro-4-boronobenzoic acid methylamide
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Methylcarbamoyl)Benzeneboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.