Description

4-(3-(Trifluoromethyl)Pyridin-2-Yl)Benzoic Acid is a high-value, multi-functional organic building block characterized by its benzoic acid core and trifluoromethylpyridine moiety. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by research institutions and manufacturers in the life sciences sector, particularly those developing novel active ingredients for medicinal and crop protection applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in kinase inhibitor and receptor modulator programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its aromatic and fluorinated components.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production.

Basic Information

Product Name	4-(3-(Trifluoromethyl)Pyridin-2-Yl)Benzoic Acid
CAS No.	847446-88-2
Molecular Formula	C13H8F3NO2
Molecular Weight	267.21 g/mol
Synonyms	2-[4-(Trifluoromethyl)pyridin-3-yl]benzoic acid; 4-(3-Trifluoromethyl-2-pyridinyl)benzoic acid; Benzoic acid, 4-[3-(trifluoromethyl)-2-pyridinyl]-; 847446-88-2; 4-(3-(Trifluoromethyl)-2-pyridyl)benzoic acid; 4-(3-Trifluoromethylpyridin-2-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-(3-(Trifluoromethyl)Pyridin-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is compatible with strong acid/organic solvent environments but should be kept separate from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.