Description

(S)-(-)-2-(1-Methoxy-1,1-Diphenylmethyl)-Pyrrolidine is a chiral pyrrolidine derivative of significant importance in asymmetric synthesis. This compound serves as a highly effective chiral auxiliary and ligand, enabling the production of enantiomerically pure intermediates critical for advanced pharmaceutical development. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the synthesis of active pharmaceutical ingredients (APIs) and other high-value chiral molecules.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including additions and cross-couplings.
• Employed as a chiral auxiliary in stereoselective organic synthesis to control the configuration of new stereocenters.
• Key building block in the research and development of pharmaceutical intermediates and active ingredients.
• Used in the synthesis of agrochemicals and other specialty chemicals requiring high enantiomeric purity.
• Facilitates method development in academic and industrial chemistry laboratories.
• Potential application in the preparation of chiral ionic liquids or catalysts.

Basic Information

Product Name	(S)-(-)-2-(1-Methoxy-1,1-Diphenylmethyl)-Pyrrolidine
CAS No.	847375-00-2
Molecular Formula	C18H21NO
Molecular Weight	267.37 g/mol
Synonyms	(S)-2-(1-Methoxy-1,1-diphenylmethyl)pyrrolidine; (S)-(-)-2-(Methoxydiphenylmethyl)pyrrolidine; (S)-MDPP; (S)-α-Methoxy-α-phenylbenzenemethanamine (pyrrolidine derivative); (S)-2-[(Methoxydiphenyl)methyl]pyrrolidine; Pyrrolidine, 2-[(methoxydiphenyl)methyl]-, (2S)-; (S)-(-)-2-(Methoxydiphenylmethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-(1-Methoxy-1,1-Diphenylmethyl)-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided to guarantee consistent quality and reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.