Description

5-(3,5-Difluorophenyl)-5-Oxovaleric Acid is a high-purity, versatile organic building block featuring a difluorophenyl moiety and a keto-acid functional group. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development, where its structure serves as a key intermediate. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the biological activity of the difluorophenyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors and specialty polymers where fluorinated aromatic units enhance stability and performance.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Bioconjugation & Probe Development: The carboxylic acid group allows for conjugation to biomolecules, making it useful in creating fluorescent probes or diagnostic agents.

Basic Information

Product Name	5-(3,5-Difluorophenyl)-5-Oxovaleric Acid
CAS No.	845790-50-3
Molecular Formula	C11H10F2O3
Molecular Weight	228.19 g/mol
Synonyms	5-Oxo-5-(3,5-difluorophenyl)pentanoic Acid; 3,5-Difluoro-γ-oxobenzenebutanoic Acid; 4-(3,5-Difluorobenzoyl)butyric Acid; 5-(3,5-Difluorobenzoyl)valeric Acid; Levulinic acid, 5-(3,5-difluorophenyl)-; 845790-50-3; 5-(3,5-Difluorophenyl)-5-oxopentanoic Acid
EINECS	Contact for details

Quality Control

Every batch of 5-(3,5-Difluorophenyl)-5-Oxovaleric Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure high purity and consistency for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.