Description

4-Oxo-Docosahexaenoic Acid is a specialized oxylipin derivative of the essential ω-3 fatty acid DHA (docosahexaenoic acid). This compound serves as a critical biochemical intermediate and research tool for studying lipid peroxidation pathways, inflammation, and cellular signaling mechanisms. It is primarily utilized by researchers and developers in the pharmaceutical, nutraceutical, and advanced life science sectors for drug discovery, biomarker analysis, and the synthesis of bioactive metabolites.

Application

• Biochemical Research: Used as a reference standard and key intermediate in studies of lipid peroxidation, oxidative stress, and specialized pro-resolving mediator (SPM) biosynthesis pathways.
• Pharmaceutical Development: Investigated as a potential precursor or active pharmaceutical ingredient (API) in novel anti-inflammatory and neuroprotective therapeutic agents.
• Nutraceutical & Cosmetic Science: Explored for its bioactive properties in the formulation of high-end dietary supplements and cosmeceutical products targeting skin health and inflammation.
• Analytical Standard: Serves as a high-purity calibration standard in analytical methods such as HPLC, LC-MS, and GC-MS for quantifying oxylipins in complex biological matrices.
• Synthetic Chemistry: Acts as a valuable building block for the organic synthesis of more complex lipid-derived molecules and analogs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Oxo-Docosahexaenoic Acid
CAS No.	845673-74-7
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	4-Oxo-DHA; 4-Oxo-docosa-4,7,10,13,16,19-hexaenoic acid; 4-Oxodocosahexaenoic Acid; 22:6-4-Oxo FA; 4-Oxo-7,10,13,16,19-docosapentaenoic Acid; (4E,7Z,10Z,13Z,16Z,19Z)-4-Oxodocosa-4,7,10,13,16,19-hexaenoic Acid
EINECS	Contact for details

Quality Control

Our 4-Oxo-Docosahexaenoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in ethanol, DMSO, and organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.