Description

3,3',4,5-Tetrafluorobenzophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of pharmaceuticals, agrochemicals, and specialty polymers, where the introduction of fluorine atoms is used to fine-tune molecular properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorination improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Polymer Modification: Incorporated into polymer backbones to enhance chemical resistance, thermal stability, and optical properties of engineering plastics.
• Organic Electronic Materials: Utilized in the development of electron-transport layers and other components for OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent for exploring new fluorination reactions and constructing complex fluorinated aromatic systems in academic and industrial labs.

Basic Information

Product Name	3,3',4,5-Tetrafluorobenzophenone
CAS No.	844885-15-0
Molecular Formula	C13H6F4O
Molecular Weight	254.18 g/mol
Synonyms	Benzophenone, 3,3',4,5-tetrafluoro-; 3,3',4,5-Tetrafluorobenzophenone; 1,3-Bis(3,4-difluorophenyl)propan-1-one (tautomeric form); Tetrafluorobenzophenone; 3,3',4,5-Tetrafluorodiphenylmethanone; (3,4-Difluorophenyl)(3,5-difluorophenyl)methanone; NSC 405124; CAS 844885-15-0
EINECS	Contact for details

Quality Control

Our 3,3',4,5-Tetrafluorobenzophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.