Description

Benzoic Acid, 3-Fluoro-5-Hydroxy-4-Methoxy-, Methyl Ester (9Ci) is a fluorinated benzoate derivative, a high-value synthetic intermediate prized for its unique substitution pattern. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic display and lighting materials.
• Polymer Modification: Incorporated as a functional monomer to impart specific solubility, thermal, or optical properties to specialty polymers.
• Chemical Research: A versatile scaffold in medicinal and synthetic chemistry for structure-activity relationship (SAR) studies.
• Complex Ligand Synthesis: Used to prepare sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Benzoic Acid, 3-Fluoro-5-Hydroxy-4-Methoxy-, Methyl Ester (9Ci)
CAS No.	838856-88-5
Molecular Formula	C9H9FO4
Molecular Weight	200.16 g/mol
Synonyms	Methyl 3-fluoro-5-hydroxy-4-methoxybenzoate; 3-Fluoro-5-hydroxy-4-methoxybenzoic acid methyl ester; Benzoic acid, 3-fluoro-5-hydroxy-4-methoxy-, methyl ester; 838856-88-5; Methyl 3-fluoro-4-methoxy-5-hydroxybenzoate; 4-Methoxy-3-fluoro-5-hydroxybenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of our Benzoic Acid, 3-Fluoro-5-Hydroxy-4-Methoxy-, Methyl Ester (9Ci) is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C/59-77°F). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.