Description

2-Naphthalenecarboxaldehyde,5-Amino-5,6,7,8-Tetrahydro-,(5R)-(9Ci) is a chiral, amino-substituted tetrahydro-2-naphthaldehyde derivative, a sophisticated building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the production of complex, biologically active molecules, offering a defined stereocenter for constructing specific three-dimensional architectures. It is primarily needed by research and development chemists and process development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex, stereochemically defined molecules.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in catalytic asymmetric reactions to introduce stereoselectivity into target compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Agrochemical Development: Serves as an intermediate in the synthesis of advanced, chiral active ingredients for crop protection products.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high purity and specific stereochemistry.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting research in organic methodology and complex molecule synthesis.

Basic Information

Product Name	2-Naphthalenecarboxaldehyde,5-Amino-5,6,7,8-Tetrahydro-,(5R)-(9Ci)
CAS No.	828926-47-2
Molecular Formula	C₁₁H₁₃NO
Molecular Weight	175.23 g/mol
Synonyms	(5R)-5-Amino-5,6,7,8-tetrahydro-2-naphthaldehyde; (R)-5-Amino-5,6,7,8-tetrahydro-2-naphthalenecarboxaldehyde; 5-Amino-5,6,7,8-tetrahydro-2-naphthaldehyde, (5R)-; 5-Amino-5,6,7,8-tetrahydro-2-naphthalenecarboxaldehyde, (R)-; 828926-47-2; (R)-5-Amino-5,6,7,8-tetrahydro-2-naphthaldehyde; Tetrahydro-2-naphthaldehyde, 5-amino-, (5R)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 2-Naphthalenecarboxaldehyde,5-Amino-5,6,7,8-Tetrahydro-,(5R)-(9Ci) is characterized and controlled using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) with detailed specifications are available upon request. We adhere to cGMP principles for the manufacture of pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; containers must be kept tightly sealed and purged after each use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.