Description

Faldaprevir is a potent and selective inhibitor of the hepatitis C virus (HCV) NS3/4A protease, a key enzyme essential for viral replication. This compound is of significant interest in pharmaceutical research and development for the treatment of chronic hepatitis C infection. It is primarily utilized by pharmaceutical companies, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in antiviral drug discovery and advanced intermediate synthesis.

Application

• Pharmaceutical Active Ingredient (API): Core component in the research and development of direct-acting antiviral (DAA) therapies for Hepatitis C Virus (HCV).
• Biochemical Research: Used as a reference standard and tool compound in virology studies to investigate HCV protease function and inhibition mechanisms.
• Process Chemistry & Intermediate: Serves as a critical advanced intermediate in the synthesis of complex antiviral drug candidates.
• Analytical Standard: Employed in quality control laboratories for method development, validation, and assay calibration in pharmaceutical analysis.

Basic Information

Product Name	Faldaprevir
CAS No.	801283-95-4
Molecular Formula	C₃₅H₄₅F₃N₆O₉S
Molecular Weight	782.83 g/mol
Synonyms	BI 201335; BI-201335; BILN 2061 analog; (1R,3aR,6aS)-2-[(2S)-2-[[(2S,3S)-1-[(2S)-2-[[(cyclopropylsulfonyl)amino]carbonyl]-1-azetidinyl]-3-methyl-1-oxo-2-pentanyl]amino]-3,3-dimethyl-1-oxobutyl]-N-[(3R)-1-(cyclopropylmethyl)-2,3-dihydro-2-oxo-5H-1,4-benzodiazepin-3-yl]-3a,4,5,6,6a,7-hexahydro-1H-cyclopenta[c]pyrrole-5-carboxamide; 1H-Cyclopenta[c]pyrrole-5-carboxamide, 3a,4,5,6,6a,7-hexahydro-2-[(2S)-2-[[(2S,3S)-1-[(2S)-2-[[(cyclopropylsulfonyl)amino]carbonyl]-1-azetidinyl]-3-methyl-1-oxo-2-pentanyl]amino]-3,3-dimethyl-1-oxobutyl]-N-[(3R)-1-(cyclopropylmethyl)-2,3-dihydro-2-oxo-5H-1,4-benzodiazepin-3-yl]-, (1R,3aR,6aS)-
EINECS	Contact for details

Quality Control

Our Faldaprevir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by spectroscopic methods (IR, NMR, MS), to ensure it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.