Description

Tazobactam Acid CAS NO 89786-04-9 is a potent β-lactamase inhibitor used in combination with β-lactam antibiotics to combat bacterial resistance. Its primary value lies in extending the spectrum and efficacy of antibiotics like piperacillin against resistant pathogens. This compound is essential for pharmaceutical manufacturers developing combination antibacterial drugs, particularly for hospital-acquired infections.

Application

• Active Pharmaceutical Ingredient (API) in combination antibacterial drugs, most notably with piperacillin as Piperacillin/Tazobactam.
• Critical component in sterile injectable formulations for the treatment of severe intra-abdominal, skin, and urinary tract infections.
• Used in pharmaceutical R&D for developing new β-lactam/β-lactamase inhibitor combinations to address evolving antimicrobial resistance.
• Key intermediate in the synthesis of more advanced or salt-form β-lactamase inhibitors.
• Reference standard in analytical laboratories for quality control and method development of antibiotic products.

Basic Information

Product Name	Tazobactam Acid
CAS No.	89786-04-9
Molecular Formula	C10H12N4O5S
Molecular Weight	300.29 g/mol
Synonyms	Tazobactam; Tazobactam Free Acid; (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; YTR 830H; CL 298741; Zosyn component; TAZ; TZP
EINECS	Contact for details

Quality Control

Our Tazobactam Acid is manufactured under strict quality systems suitable for pharmaceutical applications. It is tested to meet stringent purity criteria, with specifications aligned with major pharmacopoeial standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to ensure regulatory compliance and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.