Description

Tazobactam is a potent and highly specific β-lactamase inhibitor, crucial for combating antibiotic resistance. Its primary value lies in its synergistic action with β-lactam antibiotics, such as piperacillin, to restore their efficacy against resistant bacterial strains. This compound is essential for the pharmaceutical industry, specifically in the formulation of critical injectable combination antibiotics used in hospital settings to treat severe infections. Tazobactam CAS NO 89786-04-0 is a key active pharmaceutical ingredient (API) for manufacturers of sterile injectable drugs.

Application

• Pharmaceutical API: Primary use as the β-lactamase inhibitor component in combination antibiotic drugs, most notably with piperacillin (Piperacillin/Tazobactam).
• Injectable Formulations: Manufacture of sterile, lyophilized powders or solutions for intravenous administration in hospital-acquired and complicated infections.
• Antibiotic Resistance Management: Critical tool in antimicrobial stewardship programs to extend the lifespan and effectiveness of existing β-lactam antibiotics.
• Research & Development: Used in microbiological research and the development of new antibacterial therapies and combination products.
• Veterinary Pharmaceuticals: Potential application in advanced veterinary medicines for treating resistant bacterial infections in animals.

Basic Information

Item	Details
Product Name	Tazobactam
CAS No.	89786-04-0
Molecular Formula	C10H12N4O5S
Molecular Weight	300.29 g/mol
Synonyms	(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; YTR 830; CL 298741; Tazobactam Acid; Tazobactamum; TAZ; Zosyn (component); Piperacillin/Tazobactam (component)
EINECS	Contact for details

Quality Control

Our Tazobactam is manufactured under strict quality systems. It undergoes comprehensive analytical testing to meet high-purity standards suitable for pharmaceutical use, including specifications for assay, related substances, residual solvents, and microbiological quality. A Certificate of Analysis (COA) is provided with each batch, detailing compliance with agreed specifications. We support audits and can provide regulatory documentation as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under controlled humidity conditions. Recommended long-term storage temperature is 2-8°C. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/ USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.