Description

Tazobactam Sodium CAS NO 89785-84-2 is a potent and specific β-lactamase inhibitor used in combination with β-lactam antibiotics. Its primary value lies in restoring the efficacy of antibiotics like piperacillin against resistant bacterial strains by inhibiting a broad spectrum of β-lactamase enzymes. This compound is essential for the pharmaceutical industry, specifically in the formulation of critical injectable antibacterial combination drugs for hospital use.

Application

• Primary use as a β-lactamase inhibitor in combination antibiotic therapies, most notably with Piperacillin.
• Active pharmaceutical ingredient (API) in the manufacture of sterile injectable formulations for hospital settings.
• Critical component in drugs targeting serious infections caused by multi-drug resistant bacteria, including nosocomial pneumonia, intra-abdominal infections, and complicated urinary tract infections.
• Used in pharmaceutical research and development for novel antibiotic combination products.
• Reference standard material for analytical testing and quality control in pharmaceutical laboratories.
• Essential for compounding pharmacies requiring specific antibiotic formulations for patient-specific treatment plans.

Basic Information

Product Name	Tazobactam Sodium
CAS No.	89785-84-2
Molecular Formula	C10H11N4NaO5S
Molecular Weight	322.27 g/mol
Synonyms	Tazobactam Sodium Salt; (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide sodium salt; YTR 830H Sodium; CL 298741 Sodium; Sodium (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4λ⁶-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; Tazobactam Na; TZP Component
EINECS	Contact for details

Quality Control

Our Tazobactam Sodium is manufactured under strict quality systems, targeting compliance with major pharmacopeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing including assay, impurity profiling, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical active ingredients. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support audits and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider conditions with low humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
pH (10% solution)	4.5 - 6.5
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 0.05 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.