Description

Cyclosporin Am 9 CAS NO 89270-25-7 is a high-purity, semi-synthetic derivative of the potent immunosuppressive agent Cyclosporin A. This compound is critical for research and development in advanced immunology and pharmaceutical applications, offering a valuable tool for studying cellular mechanisms and developing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of reference standards and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the development of new immunosuppressive drugs and therapies.
• Immunology Studies: Used in laboratory research to investigate T-cell function, cytokine modulation, and other immune response pathways.
• Metabolite Analysis: Employed as an analytical standard for the quantification and characterization of Cyclosporin metabolites in biological samples.
• API Manufacturing: Acts as a critical starting material or intermediate in the synthesis of specialized pharmaceutical compounds.
• Quality Control & Assurance: Functions as a certified reference material (CRM) for calibrating equipment and validating analytical methods in QC labs.
• Preclinical Studies: Utilized in animal models to study the pharmacokinetics, efficacy, and safety profiles of novel cyclosporin analogs.

Basic Information

Product Name	Cyclosporin Am 9
CAS No.	89270-25-7
Molecular Formula	C62H111N11O12
Molecular Weight	1202.6 g/mol
Synonyms	Cyclosporin Am9; Cyclosporin A Metabolite 9; AM9; (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(1R,2R,6S)-1-hydroxy-2-methyl-6-(1-methylethenyl)-4-cyclohexen-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone; CsA-M9; Cyclosporine AM9; Cyclosporin Metabolite AM 9
EINECS	Contact for details

Quality Control

Our Cyclosporin Am 9 is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development purposes. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.