Description

L-Serine(3-13C) CAS NO 89232-77-9 is a stable isotope-labeled analog of the essential amino acid L-serine, specifically enriched with carbon-13 at the 3-position. This compound is a critical tool for advanced research and development, enabling precise metabolic pathway tracing and quantitative analysis in complex biological systems. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and life science research sectors for applications in drug metabolism studies, proteomics, and NMR spectroscopy.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to study central carbon metabolism, glycolysis, and serine biosynthesis pathways in cell cultures and microorganisms.
• Drug Discovery & Development: Essential for investigating the metabolic fate and pharmacokinetics (PK/ADME) of new drug candidates in preclinical studies.
• Quantitative Proteomics & Mass Spectrometry: Serves as a stable isotope internal standard for the accurate quantification of proteins, peptides, and metabolites.
• NMR Spectroscopy: Provides a non-radioactive, sensitive label for structural elucidation and dynamic studies of biomolecules.
• Nutritional & Biomedical Research: Employed in studies of one-carbon metabolism, neurotransmitter synthesis (e.g., glycine, D-serine), and related disorders.
• Biochemical Reagent Manufacturing: Incorporated into custom media formulations, diagnostic kits, and labeled biochemicals for research use.

Basic Information

Product Name	L-Serine(3-13C)
CAS No.	89232-77-9
Molecular Formula	C313CH7NO3
Molecular Weight	106.10 g/mol (approx.)
Synonyms	(2S)-2-Amino-3-((13)C)hydroxypropanoic acid; L-Serine-3-(13)C; L-3-((13)C)Serine; Serine-3-(13)C; (S)-2-Amino-3-((13)C)hydroxypropionic acid; (S)-Serine-3-(13)C; 13C Labeled L-Serine; L-Serine (3-13C)
EINECS	Contact for details

Quality Control

Our L-Serine(3-13C) is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % 13C), chemical purity (by HPLC), chiral purity, and specific tests for identity. We support compliance with relevant standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (atom % 13C)	≥ 99%
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.