Description

L-Serine (2-13C) is a stable isotope-labeled analog of the essential amino acid L-serine, specifically enriched with carbon-13 at the 2-position. This compound is a critical tool for advanced research and development, enabling precise metabolic pathway tracing and quantification in complex biological systems. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug metabolism studies, proteomics, and NMR spectroscopy.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to study central carbon metabolism, glycolysis, and serine biosynthesis pathways in cells and microorganisms.
• Drug Discovery & Development: Essential for investigating the metabolic fate and pharmacokinetics of new drug candidates in preclinical studies.
• Proteomics & Mass Spectrometry: Serves as an internal standard for the accurate quantification of proteins and peptides using LC-MS/MS techniques.
• NMR Spectroscopy: Provides a non-radioactive, stable isotopic label for structural elucidation and dynamic studies of biomolecules.
• Nutritional & Biomedical Research: Employed in studies of human and animal metabolism, including research into neurological disorders and cellular signaling.
• Biochemical Reagent Manufacturing: Incorporated into the production of labeled media, diagnostic kits, and other high-purity biochemical reagents.

Basic Information

Product Name	L-Serine (2-13C)
CAS No.	89232-76-8
Molecular Formula	C313CH7NO3
Molecular Weight	106.09 g/mol
Synonyms	(2S)-2-Amino-3-hydroxy(2-13C)propanoic acid; L-Serine-2-13C; (S)-Serine-2-13C; Serine-2-13C; (S)-2-Amino-3-hydroxypropionic acid-2-13C; 13C Labeled L-Serine; L-2-Amino-3-hydroxypropionic acid-2-13C
EINECS	Contact for details

Quality Control

Our L-Serine (2-13C) is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity (by HPLC), and specific analytical data. We adhere to relevant standards for high-purity biochemicals to guarantee reliable and reproducible performance in sensitive analytical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Optical Rotation	+13.5° to +15.5° (c=1 in 1N HCl)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.