Description

7,8-Epoxy-Vitamin D3 is a key synthetic intermediate in the production of various vitamin D analogs and active pharmaceutical ingredients (APIs). This compound matters for its crucial role in the synthesis of calcitriol and other high-value metabolites used in therapeutic applications. It is primarily needed by pharmaceutical manufacturers, research institutions, and fine chemical producers engaged in developing treatments for osteoporosis, psoriasis, and other conditions related to vitamin D metabolism.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active vitamin D metabolites like calcitriol (1,25-dihydroxyvitamin D3) and its analogs.
• Research & Development: Used in biochemical and pharmacological research to study vitamin D pathways, receptor binding, and metabolic activation.
• Fine Chemical Synthesis: Serves as a versatile precursor in multi-step organic syntheses for creating novel steroidal compounds.
• Nutraceutical Ingredient Development: Employed in the research phase for developing advanced vitamin D-based nutritional supplements.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for HPLC or LC-MS methods.

Basic Information

Product Name	7,8-Epoxy-Vitamin D3
CAS No.	89231-90-3
Molecular Formula	C₂₇H₄₂O₂
Molecular Weight	398.63 g/mol
Synonyms	7,8-Epoxycholecalciferol; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3β-ol, 7,8-epoxy-; Vitamin D3 7,8-epoxide; 7,8-Epoxy-9,10-secocholesta-5,7,10(19)-trien-3β-ol; Previtamin D3 7,8-epoxide
EINECS	Contact for details

Quality Control

Our 7,8-Epoxy-Vitamin D3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.