Description

(S)-15-Deoxyspergualin CAS NO 89149-10-0 is a potent synthetic derivative of the natural product spergualin, characterized by its specific stereochemistry at the 15-position. This compound is a critical immunosuppressive agent and immunomodulator, valued for its targeted mechanism of action in regulating immune responses. It is primarily required by pharmaceutical research and development teams, biotechnology companies, and advanced academic laboratories focused on immunology, autoimmune disease research, and organ transplantation studies.

Application

• Immunosuppressive Research: A key investigative tool for studying the prevention of graft rejection in organ and tissue transplantation models.
• Autoimmune Disease Studies: Used in preclinical research for conditions like lupus, rheumatoid arthritis, and multiple sclerosis to understand and modulate pathological immune activity.
• Pharmaceutical Intermediate: Serves as a high-value building block in the synthesis of more complex immunomodulatory drug candidates.
• Biochemical Mechanism Research: Employed to investigate the inhibition of nuclear factor-kappa B (NF-κB) and other intracellular signaling pathways involved in inflammation.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method development of related pharmaceutical products.

Basic Information

Product Name	(S)-15-Deoxyspergualin
CAS No.	89149-10-0
Molecular Formula	C17H37N7O4
Molecular Weight	403.53 g/mol
Synonyms	(15S)-15-Deoxyspergualin; (-)-15-Deoxyspergualin; Gusperimus; Spanidin; 1-Amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione; (S)-1-Amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione; DSG; 15-DSG
EINECS	Contact for details

Quality Control

Our (S)-15-Deoxyspergualin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S)-enantiomer
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.