Description

5-Oxo-5-(4-Trifluoromethylphenyl)Valeric Acid is a high-value trifluoromethyl-substituted organic acid building block. This compound is essential for its role in introducing the trifluoromethylphenyl moiety, a key pharmacophore known to enhance metabolic stability and lipophilicity in active molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in areas targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Advanced Polymer Modification: Incorporation into polymer chains to impart specific chemical resistance, thermal stability, or unique surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke, high-value intermediates under cGMP or other stringent quality frameworks.

Basic Information

Product Name	5-Oxo-5-(4-Trifluoromethylphenyl)Valeric Acid
CAS No.	88699-88-1
Molecular Formula	C12H11F3O3
Molecular Weight	260.21 g/mol
Synonyms	5-Oxo-5-[4-(trifluoromethyl)phenyl]pentanoic acid; 4-(4-Trifluoromethylbenzoyl)butyric acid; 5-(4-Trifluoromethylphenyl)-5-oxopentanoic acid; γ-Oxo-4-(trifluoromethyl)benzenebutanoic acid; 4-(4-Trifluoromethylphenyl)-4-oxobutanoic acid (common misnomer); 5-Oxo-5-(4-trifluoromethylphenyl)valeric acid; 4-(4-Trifluoromethylbenzoyl)butanoic acid; 88699-88-1
EINECS	Contact for details

Quality Control

Every batch of 5-Oxo-5-(4-Trifluoromethylphenyl)Valeric Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.