Description

Tazobactam is a potent β-lactamase inhibitor used in combination with β-lactam antibiotics to combat resistant bacterial infections. Its primary value lies in restoring the efficacy of antibiotics like piperacillin against a broad spectrum of pathogens, including those producing extended-spectrum β-lactamases (ESBLs). This compound is essential for the pharmaceutical industry in the development and manufacture of critical combination therapies for hospital and clinical use.

Application

• Active Pharmaceutical Ingredient (API) in combination antibiotic drugs, most notably with piperacillin.
• Critical component in the formulation of injectable antibacterial preparations for hospital use.
• Used in research and development of new antibiotic-inhibitor combinations to address antimicrobial resistance (AMR).
• Essential for the production of generic and branded pharmaceutical products targeting severe infections.
• Applied in microbiological studies to understand and combat β-lactamase-mediated resistance mechanisms.

Basic Information

Product Name	Tazobactam
CAS No.	87579-79-1
Molecular Formula	C10H12N4O5S
Molecular Weight	300.29 g/mol
Synonyms	Tazobactam Acid; Tazobactam Free Acid; (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; YTR 830H; CL 298741; Zosyn component; Piperacillin/Tazobactam component
EINECS	Contact for details

Quality Control

Our Tazobactam is manufactured and tested under strict quality systems to meet the rigorous standards required for pharmaceutical applications. We provide material that conforms to relevant pharmacopeial specifications (e.g., USP, EP) for identity, purity, and potency. A comprehensive Certificate of Analysis (COA) detailing all test results, including assay, related substances, residual solvents, and microbiological quality, is provided with each batch to ensure full traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%
Microbiological Quality	Meets Ph. Eur. requirements for non-sterile substances

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.