Description

Dezaguanine CAS NO 87434-82-0 is a synthetic purine nucleoside analog with significant biological activity. This compound is valued for its role as a key intermediate and active pharmaceutical ingredient (API) in the research and development of antiviral and anticancer therapeutics. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of novel nucleoside-based drugs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced antiviral and antineoplastic agents.
• Biochemical Research: Used as a reference standard and tool compound in studies of nucleoside metabolism and enzyme inhibition.
• Antiviral Drug Development: Serves as a precursor for compounds targeting viral polymerases and reverse transcriptases.
• Oncology Research: Investigated for its potential to interfere with DNA synthesis and repair in cancer cell lines.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of specialized nucleoside derivatives.

Basic Information

Product Name	Dezaguanine
CAS No.	87434-82-0
Molecular Formula	C10H13N5O4
Molecular Weight	267.24 g/mol
Synonyms	9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one; 2-Amino-9-β-D-ribofuranosylpurin-6(1H)-one; 2-Amino-9-β-D-ribofuranosyl-6-purinone; 9-β-D-Ribofuranosyl-2-aminopurin-6-one; Dezaguanosine; NSC 684954; 2-Aminonebularine
EINECS	Contact for details

Quality Control

Our Dezaguanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) documenting compliance with in-house specifications are available upon request. We support development and cGMP-grade production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.