Description

(+)-Noe'S Reagent CAS NO 87248-50-8 is a high-purity chiral reagent, specifically the (+)-enantiomer of a compound used for the optical resolution of racemic mixtures. This reagent is critical for producing enantiomerically pure intermediates in pharmaceutical synthesis and advanced material research. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical industries where precise stereochemistry is essential for product efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate Synthesis: Key chiral resolving agent for the production of single-enantiomer active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis Research: Used as a chiral auxiliary or ligand in the development of novel asymmetric synthetic methodologies.
• Agrochemical Development: Employed in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Critical for manufacturing high-value chiral compounds used in flavors, fragrances, and electronic chemicals.
• Academic & Industrial R&D: A standard reagent for method development and stereochemical studies in chemistry departments and corporate labs.
• Quality Control & Reference Standards: Serves as a high-purity reference material for analytical method validation and regulatory submissions.

Basic Information

Item	Details
Product Name	(+)-Noe'S Reagent
CAS No.	87248-50-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(+)-Noe's Reagent; 1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate; (R)-(+)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate; (R)-(+)-BINOL phosphate; (R)-1,1'-Bi-2-naphthol hydrogenphosphate; (R)-BINOL phosphate; (R)-VAPOL phosphate; Noe's Chiral Phosphoric Acid
EINECS	Contact for details

Quality Control

Our (+)-Noe'S Reagent is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Production adheres to cGMP guidelines where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and key impurity profiles. We support regulatory documentation needs for pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.